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1

Chemical carcinogens a review and analysis of the literature of selected chemicals and the establishment of the Gene-Tox carcinogen data base: A report of the U.S. environmental protection agency Gene-Tox program

S. Nesnow, M. Argus, H. Bergman, K. Chu, C. Frith, T. Helmes, R. McGaughy, V. Ray, T.J. Slaga, R. Tennant, E. Weisburger

Journal:

Mutation Research/Reviews in Genetic Toxicology

Year:

1987

Language:

english

File:

PDF, 8.42 MB

english, 1987

2

Comparative Potency Method for Cancer Risk Assessment: Application to Diesel Particulate Emissions

Roy E. Albert, Joellen Lewtas, Stephen Nesnow, Todd W. Thorslund, Elizabeth Anderson

Journal:

Year:

1983

Language:

english

File:

PDF, 1.40 MB

english, 1983

3

Three conazoles increase hepatic microsomal retinoic acid metabolism and decrease mouse hepatic retinoic acid levels in vivo

Pei-Jen Chen, William T. Padgett, Tanya Moore, Witold Winnik, Guy R. Lambert, Sheau-Fung Thai, Susan D. Hester, Stephen Nesnow

Journal:

Toxicology and Applied Pharmacology

Year:

2009

Language:

english

File:

PDF, 619 KB

english, 2009

4

A Comparative Potency Method for Cancer Risk Assessment: Clarification of the Rationale, Theoretical Basis, and Application to Diesel Particulate Emissions

Joellen Lewtas, Stephen Nesnow, Roy E. Albert

Journal:

Year:

1983

Language:

english

File:

PDF, 420 KB

english, 1983

5

Proteomic Analysis of Propiconazole Responses in Mouse Liver: Comparison of Genomic and Proteomic Profiles

Ortiz, Pedro A., Bruno, Maribel E., Moore, Tanya, Nesnow, Stephen, Winnik, Witold, Ge, Yue

Journal:

Journal of Proteome Research

Year:

2010

Language:

english

File:

PDF, 4.56 MB

english, 2010

6

Propiconazole Induces Alterations in the Hepatic Metabolome of Mice: Relevance to Propiconazole-Induced Hepatocarcinogenesis

Nesnow, S., Padgett, W. T., Moore, T.

Journal:

Toxicological Sciences

Year:

2011

Language:

english

File:

PDF, 612 KB

english, 2011

7

Thirteenth Aspen Cancer Conference: Workshop on Mechanisms of Toxicity and Carcinogenesis

Stephen Nesnow, Webster Cavanee, Tona M. Gilmer, David G. Kaufman, Thomas J. Slaga, Robert Hohman, J. Michael Bishop, Miriam C. Poirier, Curtis C. Harris, Benjamin F. Trump, Stuart H. Yuspa, Andrea M.

Journal:

Molecular Carcinogenesis

Year:

1999

Language:

english

File:

PDF, 65 KB

english, 1999

8

Synergism in the transformation of hamster embryo cells treated with formaldehyde and adenovirus

George G. Hatch, Patricia M. Conklin, Carla C. Christensen, Bruce C. Casto, Stephen Nesnow

Journal:

Environmental and Molecular Mutagenesis

Year:

1983

Language:

english

File:

PDF, 563 KB

english, 1983

9

Mutation and enhanced virus transformation of cultured hamster cells by exposure to gaseous ethylene oxide

Dr. George G. Hatch, Patricia M. Conklin, Carla C. Christensen, Tara M. Anderson, Robert Langenbach, Stephen Nesnow

Journal:

Environmental and Molecular Mutagenesis

Year:

1986

Language:

english

File:

PDF, 651 KB

english, 1986

10

Transfection of a Rat Cytochrome P450b cDNA Into C3H10T1/2CL8 Mouse Embryo Fibroblasts

Suzanne K. Hansen, Jeffrey A. Ross, Jill M. Siegfried, Sharon Leavitt, Kenneth Rudo, Robert Langenbach, Stephen Nesnow

Journal:

Molecular Carcinogenesis

Year:

1989

Language:

english

File:

PDF, 680 KB

english, 1989

11

Ki-ras oncogene mutations in tumors and DNA adducts formed by benz[j]aceanthrylene and benzo[a]pyrene in the lungs of strain A/J mice

Marc J. Mass, Jeffrey A. Ross, Stephen Nesnow, Anita J. Jeffers, Garret Nelson, Anthony J. Galati, Gary D. Stoner

Journal:

Molecular Carcinogenesis

Year:

1993

Language:

english

File:

PDF, 623 KB

english, 1993

12

Quantitative Analysis of Alachlor Protein Adducts by Gas Chromatography–Mass Spectrometry

Guy R. Lambert, William T. Padgett, Michael H. George, Kirk T. Kitchin, Stephen Nesnow

Journal:

Analytical Biochemistry

Year:

1999

Language:

english

File:

PDF, 92 KB

english, 1999

13

A rapid and sensitive liquid chromatographic assay for epoxide hydrase

S. Nesnow, C. Heidelberger

Journal:

Analytical Biochemistry

Year:

1975

Language:

english

File:

PDF, 300 KB

english, 1975

14

An improved radiochemical assay for benzo[a]pyrene monooxygenase

Stephen Nesnow, William E. Fahl, Colin R. Jefcoate

Journal:

Analytical Biochemistry

Year:

1977

Language:

english

File:

PDF, 587 KB

english, 1977

15

Mechanistic linkage between DNA adducts, mutations in oncogenes and tumorigenesis of carcinogenic environmental polycyclic aromatic hydrocarbons in strain A/J mice

Stephen Nesnow, Jeffrey A. Ross, Gary D. Stoner, Marc J. Mass

Journal:

Year:

1995

Language:

english

File:

PDF, 1.03 MB

english, 1995

16

Identification and quantitation of benzo[a]pyrene-derived DNA adducts formed at low adduction level in mice lung tissue

Marzena Banasiewicz, Garret Nelson, Adam Swank, Nenad Grubor, Jeffrey Ross, Stephen Nesnow, Harald Köfeler, Gerald J. Small, Ryszard Jankowiak

Journal:

Analytical Biochemistry

Year:

2004

Language:

english

File:

PDF, 519 KB

english, 2004

17

Benzo[a]pyrene-7,8-quinone-3′-mononucleotide adduct standards for 32P postlabeling analyses: Detection of benzo[a]pyrene-7,8-quinone–calf thymus DNA adducts

Narayanan Balu, William T. Padgett, Garret B. Nelson, Guy R. Lambert, Jeffrey A. Ross, Stephen Nesnow

Journal:

Analytical Biochemistry

Year:

2006

Language:

english

File:

PDF, 401 KB

english, 2006

18

Species variation in bladder cell and liver cell activation of acetylaminofluorene

Robert Langenbach, Kenneth Rudo, Scott Ellis, Cathy Hix, Stephen Nesnow

Journal:

Cell Biology and Toxicology

Year:

1987

Language:

english

File:

PDF, 1.04 MB

english, 1987

19

Quantitative evaluation of the effects of human carcinogens and related chemicals on human foreskin fibroblasts

Ponnamma Kurian, Stephen Nesnow, George E. Milo

Journal:

Cell Biology and Toxicology

Year:

1990

Language:

english

File:

PDF, 853 KB

english, 1990

20

In vitro toxicity screening tests: A comparison of activation systems and treatment protocols among different laboratories

Sabine H. H. Swierenga, David E. Amacher, Robert T. Christian, Joanne T. Emerman, Linda B. Jacobsen, Robert W. Naismith, Stephen Nesnow, Kenneth Palmer, Charles G. Rogers, Karl A. Traul

Journal:

Methods in Cell Science

Year:

1983

Language:

english

File:

PDF, 478 KB

english, 1983

21

Pyridine nucleosides related to 5-fluorouracil

Stephen Nesnow, Charles Heidelberger

Journal:

Journal of Heterocyclic Chemistry

Year:

1973

File:

PDF, 456 KB

1973

22

Pyridine nucleosides related to 5-fluorocytosine

Stephen Nesnow, Charles Heidelberger

Journal:

Journal of Heterocyclic Chemistry

Year:

1975

File:

PDF, 241 KB

1975

23

Quantitative analysis of the metabolism of benzo(a)pyrene by transformable C3H10T1/2CL8 mouse embryo fibroblasts

Kenneth Rudo, Scott Ellis, B. J. Bryant, Kay Lawrence, Gaynelle Curtis, Helen Garland, Stephen Nesnow

Journal:

Teratogenesis, Carcinogenesis, and Mutagenesis

Year:

1986

Language:

english

File:

PDF, 779 KB

english, 1986

24

A method for combining and comparing short-term genotoxicity test data: Preface: A report from ICPEMC Committee 1

D.J. Brusick, J. Ashby, F.J. de Serres, P.H.M. Lohman, T. Matsushima, B.E. Matter, M.L. Mendelsohn, D.H. Moore II, S. Nesnow, M.D. Waters

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

1992

Language:

english

File:

PDF, 474 KB

english, 1992

25

Metabolism of α-naphthoflavone by rat, mouse, rabbit, and hamster liver microsomes

Hinda B. Bergman, B.J. Bryant, Stephen Nesnow

Journal:

Toxicology and Applied Pharmacology

Year:

1984

Language:

english

File:

PDF, 685 KB

english, 1984

26

An approach to identifying specialized batteries of bioassays for specific classes of chemicals: Class analysis using mutagenicity and carcinogenicity relationships and phylogenetic concordance and discordance patterns 1. composition and analysis of the overall data base a report of phase II of the U.S. environmental protection agency gene-tox program (MTR 07213)

V.A. Ray, L.D. Kier, K.L. Kannan, R.T. Haas, A.E. Auletta, J.S. Wassom, S. Nesnow, M.D. Waters

Journal:

Mutation Research/Reviews in Genetic Toxicology

Year:

1987

Language:

english

File:

PDF, 2.48 MB

english, 1987

27

A multi-factor ranking scheme for comparing the carcinogenic activity of chemicals

Journal:

Mutation Research/Reviews in Genetic Toxicology

Year:

1990

Language:

english

File:

PDF, 2.00 MB

english, 1990

28

Genotoxic effects of cyclopenta-fused polyaromatic hydrocarbons in isolated rodent liver and lung cells

J.A. Holme, C. Bjørge, E.J. Søderlund, G. Brunborg, R. Becher, M. Låg, P. Schwarze, G. Nelson, J. Ross, S. Nesnow

Journal:

Mutation Research/Environmental Mutagenesis and Related Subjects

Year:

1992

Language:

english

File:

PDF, 83 KB

english, 1992

29

Correlation of carcinogenic potency with mouse-skin 32P-postlabeling and muta-Rmouse lac Z− mutation data for DMBA and its K-region sulphur isostere: comparison with activities observed in standard genotoxicity assays

J. Ashby, D. Brusick, B.C. Myhr, N.J. Jones, J.M. Parry, S. Nesnow, D. Paton, H. Tinwell, H.S. Rosenkranz, S. Curti, D. Gilman, R.D. Callander

Journal:

Mutation Research/Environmental Mutagenesis and Related Subjects

Year:

1993

Language:

english

File:

PDF, 1.21 MB

english, 1993

30

Benz[j]aceanthrylene: A novel polycyclic aromatic hydrocarbon with bacterial mutagenic activity

R. Sangaiah, A. Gold, G.E. Toney, S.H. Toney, L. Claxton, R. Easterling, S. Nesnow

Journal:

Mutation Research Letters

Year:

1983

Language:

english

File:

PDF, 353 KB

english, 1983

31

Induction of anchorage-independent growth in human diploid fibroblasts by the cyclopenta-polycyclic aromatic hydrocarbon, benz[l]aceanthrylene

Stephen Nesnow, George Milo, Ponnamma Kurian, Ramiah Sangaiah, Avram Gold

Journal:

Mutation Research Letters

Year:

1990

Language:

english

File:

PDF, 357 KB

english, 1990

32

N-Nitrosodiethylamine and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone induced morphological transformation of C3H/10T1/2CL8 cells expressing human cytochrome P450 2A6

Stephen Nesnow, Susan Beck, Suzanne Rosenblum, Jessica Lasley, Howard F. Tiano, Masakiyo Hosokawa, Charles L. Crespi, Robert Langenbach

Journal:

Mutation Research Letters

Year:

1994

Language:

english

File:

PDF, 757 KB

english, 1994

33

Role of cell signaling in B[a]P-induced apoptosis: characterization of unspecific effects of cell signaling inhibitors and apoptotic effects of B[a]P metabolites

Anita Solhaug, Steinar Øvrebø, Steen Mollerup, Marit Låg, Per E. Schwarze, Stephen Nesnow, Jørn A. Holme

Journal:

Chemico-Biological Interactions

Year:

2005

Language:

english

File:

PDF, 641 KB

english, 2005

34

Lack of contribution of covalent benzo[a]pyrene-7,8-quinone–DNA adducts in benzo[a]pyrene-induced mouse lung tumorigenesis

Stephen Nesnow, Garret Nelson, William T. Padgett, Michael H. George, Tanya Moore, Leon C. King, Linda D. Adams, Jeffrey A. Ross

Journal:

Chemico-Biological Interactions

Year:

2010

Language:

english

File:

PDF, 513 KB

english, 2010

35

Propiconazole increases reactive oxygen species levels in mouse hepatic cells in culture and in mouse liver by a cytochrome P450 enzyme mediated process

Stephen Nesnow, Rachel D. Grindstaff, Guy Lambert, William T. Padgett, Maribel Bruno, Yue Ge, Pei-Jen Chen, Charles E. Wood, Lynea Murphy

Journal:

Chemico-Biological Interactions

Year:

2011

Language:

english

File:

PDF, 761 KB

english, 2011

36

Mutagenicity, stable DNA adducts, and abasic sites induced in Salmonella by phenanthro[3,4-b]- and phenanthro[4,3-b]thiophenes, sulfur analogs of benzo[c]phenanthrene

Carol D. Swartz, Leon C. King, Stephen Nesnow, David M. Umbach, Subodh Kumar, David M. DeMarini

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

2009

Language:

english

File:

PDF, 456 KB

english, 2009

37

Corrigendum to “Mutagenicity, stable DNA adducts, and abasic sites induced in Salmonella by phenanthro[3,4-b]- and phenanthro[4,3-b] thiophenes, sulfur analogs of benzo[c]phenanthrene” [Mutat. Res. 661 (2009) 47–56]

Carol D. Swartz, Leon C. King, Stephen Nesnow, David M. Umbach, Subodh Kumar, Harish Sikka, David M. DeMarini

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

2010

Language:

english

File:

PDF, 86 KB

english, 2010

38

Transcriptional responses in thyroid tissues from rats treated with a tumorigenic and a non-tumorigenic triazole conazole fungicide

Susan D. Hester, Stephen Nesnow

Journal:

Toxicology and Applied Pharmacology

Year:

2008

Language:

english

File:

PDF, 1.64 MB

english, 2008

39

Propiconazole-enhanced hepatic cell proliferation is associated with dysregulation of the cholesterol biosynthesis pathway leading to activation of Erk1/2 through Ras farnesylation

Lynea A. Murphy, Tanya Moore, Stephen Nesnow

Journal:

Toxicology and Applied Pharmacology

Year:

2012

Language:

english

File:

PDF, 866 KB

english, 2012

40

Polycyclic aromatic hydrocarbons: correlations between DNA adducts and ras oncogene mutations

Jeffrey A Ross, Stephen Nesnow

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

1999

Language:

english

File:

PDF, 101 KB

english, 1999

41

Microsomal metabolism of benzo(a)pyrene: Multiple effects of epoxide hydrase inhibitors

William E. Fahl, Stephen Nesnow, Colin R. Jefcoate

Journal:

Archives of Biochemistry and Biophysics

Year:

1977

Language:

english

File:

PDF, 1.31 MB

english, 1977

42

Inhibition of aromatase cytochrome P-450 (estrogen synthetase) by derivatives of α-naphthoflavone

James T. Kellis Jr., Stephen Nesnow, Larry E. Vickery

Journal:

Biochemical Pharmacology

Year:

1986

Language:

english

File:

PDF, 600 KB

english, 1986

43

4-Ipomeanol and 2-aminoanthracene cytotoxicity in C3H/10T12 cells expressing rabbit cytochrome P450 4B1

P.Blaise Smith, Howard F. Tiano, Stephen Nesnow, Michael R. Boyd, Richard M. Philpot, Robert Langenbach

Journal:

Biochemical Pharmacology

Year:

1995

Language:

english

File:

PDF, 1.16 MB

english, 1995

44

Characterization of naphtho[1,2-a]pyrene and naphtho[1,2-e]pyrene DNA adducts in C3H10T1/2 fibroblasts

Garret Nelson, Jeffrey A. Ross, Maria Pimentel, Dhimant Desai, Arun K. Sharma, Shantu Amin, Stephen Nesnow

Journal:

Year:

2007

Language:

english

File:

PDF, 347 KB

english, 2007

45

Cytotoxic effects of propiconazole and its metabolites in mouse and human hepatoma cells and primary mouse hepatocytes

Pei-Jen Chen, Tanya Moore, Stephen Nesnow

Journal:

Toxicology in Vitro

Year:

2008

Language:

english

File:

PDF, 238 KB

english, 2008

46

Comparison of the genotoxic activities of the K-region dihydrodiol of benzo[a]pyrene with benzo[a]pyrene in mammalian cells: morphological cell transformation; DNA damage; and stable covalent DNA adducts

Stephen Nesnow, Christine Davis, Garret B Nelson, Guy Lambert, William Padgett, Maria Pimentel, Alan H Tennant, Andrew D Kligerman, Jeffrey A Ross

Journal:

Mutation Research/Genetic Toxicology and Environmental Mutagenesis

Year:

2002

Language:

english

File:

PDF, 194 KB

english, 2002

47

CARCINOGEN METABOLISM IN RAT LIVER CELL CULTURE,

Stephen Nesnow, Joellen Huisingh, Hinda Bergman, Robert Easterling, Jeff Inmon, Leon King, Mary S. Morris, Katherine Williams, Betty Hyatt, Linda Montgomery, Claire Cudak

Journal:

Annals of the New York Academy of Sciences

Year:

1980

Language:

english

File:

PDF, 795 KB

english, 1980

48

1,2-Naphthoquinone: A mediator of non-enzymatic benzo(a)pyrene oxidation

Stephen Nesnow, Hinda Bergman

Journal:

Year:

1979

Language:

english

File:

PDF, 273 KB

english, 1979

49

Comparative effect of pretreatment with phenobarbital, Aroclor 1254, and β-naphthoflavone on the metabolism of lindane

Robert W. Chadwick, M.Frank Copeland, M.Leonard Mole, Stephen Nesnow, Nathaniel Cooke

Journal:

Pesticide Biochemistry and Physiology

Year:

1981

Language:

english

File:

PDF, 1.11 MB

english, 1981

50

Mutagenic and carcinogenic potency of extracts of diesel and related environmental emissions: In vitro mutagenesis and oncogenic transformation

Bruce C. Casto, George G. Hatch, Shiu L. Huang, Joellen Lewtas, Stephen Nesnow, Michael D. Waters

Journal:

Environment International

Year:

1981

Language:

english

File:

PDF, 660 KB

english, 1981

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